Green synthesis of stroke treatment compounds: Methods and potential applications

Mohamed, Rogy Reda

doi:10.21608/odr.2025.380512.1051

Green synthesis of stroke treatment compounds: Methods and potential applications

Document Type : Review Articles

Author

Rogy Reda Mohamed

Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Port Said University, Port Said 42526, Egypt

10.21608/odr.2025.380512.1051

Abstract

Since Stroke is a major cause of mortality and disability worldwide, safer and more efficient treatment options must be developed. By providing an environmentally friendly substitute for conventional chemical synthesis, green chemistry makes it possible to produce stroke-treating substances with a reduced negative influence on the environment. Benzimidazole derivatives, Crocetin and related oxygen diffusion-enhancing compounds, curcumin analogues, chalcone derivatives with spiro-heterocyclic and Fluorine-containing compounds are among the compounds that have shown encouraging anti-inflammatory and neuroprotective qualities. In relation to our topic, we will go over and deepen our understanding of some of the medications used to treat stroke and how they are manufactured utilizing Green synthesis, which uses environmentally friendly resources and procedures, has emerged as a promising method for producing safer pharmaceuticals. Interestingly, environmentally friendly nanoparticles have shown promise in enhancing drug delivery, reducing adverse effects, and bridging the blood-brain barrier. This study discusses a number of green synthesis methods for compounds that have a lot of promise for treating stroke.

Highlights

Since stroke is one of the world's leading causes of death and disability, safer and more efficient treatment options must be developed.
Green synthesis marks a significant turn in the development of drugs for the treatment of stroke towards sustainable and biocompatible methods.
Greenly manufactured compounds meet safety and environmental standards while also providing medicinal advantages.
Green chemistry promises improved efficacy and fewer adverse effects when included into pharmaceutical research, which will ultimately advance neurovascular care.

Keywords

Main Subjects

Drugs from natural sources

© 2025 by the authors; licensee Port Said University, Egypt. This open-access article is distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).